Chronic obstructive pulmonary diseases in children

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Chronic obstructive pulmonary diseases in children.

OBJECTIVES To verify and describe the main events related to the diagnosis and management of chronic obstructive pulmonary diseases in children (COPDC) and adolescents, considering the interrelated physiopathology, genetic, and environmental characteristics. SOURCES Relevant literature from PubMed was selected and reviewed. SUMMARY OF THE FINDINGS COPDC have an environmental and/or genetic ...

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  Background : There is little evidence about the role of Zafirlukast (a highly selective LTD4 antagonist) in Chronic Obstructive Pulmonary Disease (COPD). The Zafirlukast can reduce the need for short-acting rescue β2 agonists, produce fewer exacerbations of asthma and increased quality of life as possible benefits treatment for asthma. The aim of our study was to evaluate the effects of Zafir...

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Biomarkers in Chronic Obstructive Pulmonary Diseases

APN circulates in different molecular forms in the blood. It has been reported by Miller et al., that by screening bronchoalveolar lavage (BAL) fluids from chronic obstructive pulmonary disease-Emphysema (COPD-E) and control subjects the epithelial cells can also secrete APN. Immuno-histochemistry of lung sections in COPD-E patients’ demonstrated markable levels of adiponectin and adiponectin r...

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Statins and Pulmonary Hypertension in Chronic Obstructive Lung Disease

Chronic obstructive lung disease (COPD) is a chronic multisystem disease with a considerable burden. One of its most common complications is pulmonary artery hypertension (PAH). It has been demonstrated that the development of PAH is correlated with decreased quality of life and survival. Different medications have been proposed for the treatment of PAH, among which one can name statins. Howeve...

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Background and Purpose: Chronic obstructive pulmonary disease (COPD) has been recognized as a risk factor for invasive aspergillosis. Airway colonization by Aspergillus species is a common feature of chronic pulmonary diseases. Nowadays, the incidence of COPD has increased in critically ill patients. The aim of the present study was to isolate and identify Aspergillus colonies in the respirator...

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ژورنال

عنوان ژورنال: Jornal de Pediatria (Versão em Português)

سال: 2015

ISSN: 2255-5536

DOI: 10.1016/j.jpedp.2015.09.007